Advances in Inorganic Chemistry : volume 61: metal Ion controlled reactivity / edited by Rudi van Eldik and Colin D. Hubbard

Front cover; Advances in Inorganic Chemistry; Copyright page; Contents; List of Contributors; Preface; Chapter 1. Controlling platinum, ruthenium, and osmium reactivity for anticancer drug design; I. Introduction; II. Platinum Anticancer Prodrugs: A Photoactivation Strategy; III. Ruthenium-Arene Anticancer Drugs; IV. Osmium(II)-Arenes: A Cytotoxic Family of the Heavier Congener; V. Concluding Remarks; Acknowledgments; References; Chapter 2. Design and function of metal complexes as contrast agents in MRI; I. Introduction; II. Relaxivity of GdIII Complexes: Optimization of the Relaxivity

III. Stability AspectsIV. Paramagnetic CEST Agents; V. Responsive Imaging Probes; VI. MnII Complexes in the Context of MRI; VII. Non-Classical GdIII-Based MRI Contrast Agents; VIII. Conclusions and Outlook; References; Chapter 3. Design considerations towards simultaneously radiolabeled and fluorescent imaging probes incorporating metallic species; I. Introduction; II. Small-Molecule Metal-Based Probes and Their Biomedical Imaging Capabilities; III. Conclusions; Acknowledgments; References

Chapter 4 .Iron sequestration by small molecules: Thermodynamic and kinetic studies of natural siderophores and synthetic model compoundsI. Chemistry of Iron and Siderophores; II. Siderophore Structure; III. Thermodynamics of Iron-Siderophore Interactions; IV. Chelation Kinetics of Iron-Siderophore Systems; V. Siderophore Recognition and Cellular Uptake; VI. Applications and Future Directions in Siderophore Research; List of Structure Numbers, Figures, and Abbreviations; Acknowledgments; References; Chapter 5. Calcium in biological systems; I. Introduction; II. The Ca2plus Aqua-Cation

III. Calcium-Binding MetalloproteinsIV. Ca2plus in Ionophores, Channels, and Pumps; V. Carbohydrates and Carboxylates; VI. Phosphates, Phosphonates, Nucleosides, and Nucleotides; VII. Stability Constants: An Overview; VIII. Calcium-Containing Rigid Materials; Ligand Abbreviations; Acknowledgments; References; Appendix: The Term Ligand; Chapter 6. New developments in synthetic nitrogen fixation with molybdenum and tungsten phosphine complexes; I. Introduction; II. Mechanism of the Chatt Cycle: Experimental Investigations; III. Mechanism of the Chatt Cycle: Theoretical Investigations

IV. Molybdenum Dinitrogen Complexes with Polydentate Phosphine and Mixed PsolN LigandsV. Conclusions; Acknowledgments; References; Chapter 7. Chemistry of metalated container molecules; I. Introduction; II. Metalated Container Molecules: Host Systems and Complex Types; II. Metalated Container Molecules of Binucleating Polyaza-Dithiophenolate Macrocycles; IV. Conclusion; Acknowledgments; References; Chapter 8. Mechanistic considerations on the reactivity of green FeIII-TAML activators of peroxides; I. Introduction

II. Speciation of Tetraamide Iron(III) Macrocycles in Solution and the Solid State

The Advances in Inorganic Chemistry series present timely and informative summaries of the current progress in a variety of subject areas within inorganic chemistry, ranging from bio-inorganic to solid state studies. This acclaimed serial features reviews written by experts in the field and serves as an indispensable reference to advanced researchers. Each volume contains an index, and each chapter is fully referenced. * Features comprehensive reviews on the latest developments * Includes contributions from leading experts in the field *