000			02939cam a22003857i 4500
001			04710
003			GSU
005			20231127180433.0
008			180119s2018 enka b 001 0 eng d
010			_a 2017448829
020			_a9781788010290 _q(hardback)
020			_a1788010299 _q(hardback)
020			_z9781788011907 _q(PDF)
020			_z9781788012232 _q(EPUB)
035			_a(OCoLC)on1014285175
040			_aYDX _beng _cYDX _erda _dHUA _dDLC _dGSU
042			_alccopycat
050	0	0	_aQD412.S5 _bJAI
082	0	4	_a547.05724 _223
245	0	0	_aOrganoselenium compounds in biology and medicine : _bsynthesis, biological and therapeutic treatments / _cedited by Vimal Kumar Jain, Bhabha Atomic Research Centre, India, and K. Indira Priyadarsini, Bhabha Atomic Research Centre, India.
264		1	_aLondon : _bThe Royal Society of Chemistry, _c©2018.
300			_axvii, 457 pages : _billustrations ; _c24 cm
336			_atext _btxt _2rdacontent
337			_aunmediated _bn _2rdamedia
338			_avolume _bnc _2rdacarrier
504			_aIncludes bibliographical references and index.
505			_aAn overview of organoselenium chemistry: From fundamentals to Synthesis; Looking Beyond the traditional Idea of Glutathione Peroxidase Mimics as Antioxidants; Synthesis of organoselenium compounds with potential biological activities; The Relevant Chemistry of Imidazoline-2-selone Donors with potential Biological Applications; Organoselenium cations: Structures, reactivity and applications; Organoselenium flurophores for probing ROS and heavy metals; Non-bonded selenium…heteroatom interactions in selenoenzymeglutathioneperoxidase (GPx) and mimics; Carbohydrate-derived Organoselenium Compounds: Synthesis and Application in the Structural Analysis of Biomolecules; Reaction of Selenium compounds with reactive oxygen species and the controlof oxidative stress; Reactive selenium species: Redox modulation, antioxidant, antimicrobial and anticancer activities; Ebselen and thioredoxin systems in human health, disease and therapeutic potential; History and development of selenium based radioprotectors: Distinction between inorganic vs. organic forms; Toxicology and anticancer activity of synthetic organoselenium compounds; Metabolism of selenium/selenocystine and their roles in the prevention and treatment of human cancer; Organoselenium compounds as cancer therapeutic agents; Cancer prevention by different forms of selenium
520			_aThis book discusses organoselenium chemistry and biology in the context of its therapeutic potential, taking the reader through synthetic techniques, bioactivity and therapeutic applications
650		0	_aOrganoselenium compounds.
700	1		_aJain, Vimal Kumar, _eeditor.
700	1		_aPriyadarsini, K. Indira, _eeditor.
906			_a7 _bcbc _ccopycat _d2 _encip _f20 _gy-gencatlg
942			_2lcc _cBK _n0
999			_c2047 _d2047