TY - BOOK AU - Ramalingam, Murugan AU - Ramakrishna,Seeram TI - Nanofiber composites for biomedical applications T2 - Woodhead Publishing series in biomaterials SN - 0081001738 AV - R857 RAM U1 - 610.28/4 23 PY - 2017///] CY - Duxford, United Kingdom PB - Woodhead Publishing, an imprint of Elsevier KW - Nanobiotechnology KW - Nanocomposites (Materials) KW - Nanostructured materials KW - Nanofibers KW - Biomedical materials KW - fast N1 - Includes bibliographical references and index; Machine generated contents note; pt. I; Introduction to nanofiber composites --; 1; Introduction to nanofiber composites; S. Ramakrishna --; 1.1; Introduction --; 1.2; Classification of nanofiber composites --; 1.3; Properties of nanofiber composites --; 1.4; Fabrication methods of nanofiber composites --; 1.5; Characterization techniques of nanofiber composites --; 1.6; Biomedical applications of nanofiber composites --; 1.7; Clinical translational aspects of nanofiber composites --; 1.8; Commercial aspects of nanofiber composites --; 1.9; Concluding remarks --; References --; pt. II; Classification of nanofiber composites --; 2; Ceramic nanofiber composites; M. Ramalingam --; 2.1; Introduction --; 2.2; Types of ceramic nanofiber composite --; 2.3; Properties of ceramic nanofiber composite --; 2.4; Fabrication methods --; 2.5; Biomedical applications of ceramic nanofiber composite --; 2.6; Concluding remarks --; References --; 3; Polymer nanofiber composites; Y.-W. Mai --; 3.1; Introduction --; 3.2; Nanofiber composites using electrospinning --; 3.3; Modified electrospinning setup for scaffold design --; 3.4; Biofunctionalization of fibrous scaffolds --; 3.5; Application of nanofiber composites --; 3.6; Future perspectives of polymer nanofiber --; Acknowledgments --; References --; 4; Metallic nanofiber composites; G. Manivasagam --; 4.1; Introduction --; 4.2; Technological aspect --; 4.3; Metallic nanofiber composite applications in bio-medical and health care --; 4.4; Conclusions and future perspectives --; References --; pt. III; Properties of nanofiber composites --; 5; Physicochemical characterization of nanofiber composites; F. Yang --; 5.1; Introduction --; 5.2; Physicochemical characterization at molecular level --; 5.3; Physicochemical characterization at surface level --; 5.4; Physicochemical characterization at materials level --; 5.5; Conclusion --; References --; 6; Mechanical characterization of nanofiber composites; M. Ramalingam --; 6.1; Introduction --; 6.2; Nanotechnology and biomedicine --; 6.3; Tissue engineering --; 6.4; Scaffolds for tissue engineering --; 6.5; Electrospinning --; 6.6; Mechanical properties of nanofibers: case studies --; 6.7; Conclusion and future direction --; Acknowledgment --; References --; 7; Biological characterization of nanofiber composites; D. Sachdev --; 7.1; Introduction --; 7.2; Morphological characterization of nano fibers --; 7.3; Biomedical applications implicated characterization --; 7.4; Cell nanofiber scaffold interactive characterization --; 7.5; Concluding remarks --; References --; pt. IV; Biomedical Applications of Nanofiber Composites --; 8; Nanofiber composites in drug delivery; S. Ramakrishna --; 8.1; Introduction --; 8.2; Implications of nanofiber-based DDS in health care --; 8.3; Composite nanofibers for drug delivery --; 8.4; Applications of composite nanofibers as DDS --; 8.5; Future prospects --; 8.6; Concluding remarks --; References --; 9; Nanofiber composites in biomolecular delivery; M. Ramalingam --; 9.1; Introduction --; 9.2; Importance of biomolecules in biomedical applications --; 9.3; Composite nanofibers for biomolecular delivery --; 9.4; Release strategy of biomolecules from composite nanofiber scaffolds --; 9.5; Applications of composite nanofibers for biomolecular delivery --; 9.6; Preclinical status --; 9.7; Concluding remarks --; References --; 10; Nanofiber composites in gene delivery; M. Ramalingam --; 10.1; Introduction --; 10.2; Nanofiber composites-mediated gene delivery --; 10.3; Fabrication methods --; 10.4; Characterization techniques --; 10.5; Classification --; 10.6; Pharmacology and kinetics: gene delivery --; 10.7; Current status --; 10.8; Conclusion --; References --; 11; Nanofiber composites in skin tissue engineering; L. Rajamani --; 11.1; Introduction --; 11.2; Skin morphology --; 11.3; Skin disorders --; 11.4; Wound healing process --; 11.5; Types of skin grafts and skin substitutes --; 11.6; Tissue engineering --; 11.7; Composite Nanofibrous Mats --; 11.8; Impact of nanofibers in skin regeneration process --; 11.9; Conclusion --; Acknowledgment --; References --; 12; Nanofiber composites in bone tissue engineering; A.R. Boccaccini --; 12.1; Introduction --; 12.2; Topic overview --; 12.3; Rationale for the selection of the inorganic phase for bone tissue engineering applications --; 12.4; Electrospinning and its integration with other scaffold fabrication techniques for bone tissue engineering --; 12.5; Three dimensional nanofibrous structures for bone tissue engineering --; 12.6; Functionalized nanofiber composites --; 12.7; In vivo applications of nanofiber composites for bone tissue regeneration --; 12.8; Conclusions --; Acknowledgements --; References --; 13; Nanofiber composites in cartilage tissue engineering; M. Ramalingam --; 13.1; Introduction --; 13.2; Microstructure of cartilage tissue --; 13.3; Composite nanofiber for cartilage regeneration --; 13.4; Biological relevance of composite nanofiber in cartilage regeneration --; 13.5; Future directions and perspectives --; References --; 14; Nanofiber composites in tendon tissue engineering; H. EI-Hamshary --; 14.1; Introduction --; 14.2; Different topological structure of nanofiber for tendon tissue regeneration --; 14.3; Development of three-dimensional scaffolds for tendon tissue engineering --; 14.4; Mechanical simulation of scaffold constructs for tendon tissue remodeling --; 14.5; Growth factors and stem cells strategies incorporated with nanofibers in tendon tissue engineering --; 14.6; Conclusion --; References --; 15; Nanofiber composites in skeletal muscle tissue engineering; J.P. Beier --; 15.1; Introduction --; 15.2; Skeletal muscle anatomy --; 15.3; Tissue engineering of skeletal muscle --; 15.4; Three-dimensional matrices for skeletal muscle tissue engineering --; 15.5; Polymeric Materials for electrospun nanofibers --; 15.6; Mechanical and electrical stimulation of engineered skeletal muscle --; 15.7; Vascularization and in vivo generation of 3D muscle constructs --; 15.8; Future aspects --; 15.9; Conclusion --; References --; 16; Nanofiber composites in neural tissue engineering; H. EI-Hamshary --; 16.1; Introduction --; 16.2; Composite nanofiber NGC --; 16.3; Nanofiber NGC with regular structure --; 16.4; Growth factor incorporated into nanofiber NTE scaffold --; 16.5; Conductive nanofiber NGC and electrical simulation for NTE --; 16.6; Conclusion --; References --; 17; Nanofiber composites in cardiac tissue engineering; D.K. Srinivasan --; 17.1; Introduction --; 17.2; Cardiac structure --; 17.3; Cardiac tissue remodeling --; 17.4; Cardiac tissue engineering --; 17.5; Fibrous scaffolds for building of cardiac tissue --; 17.6; Challenges and future trends in cardiac tissue engineering --; 17.7; Conclusion --; Acknowledgements --; References --; 18; Nanofiber composites in vascular tissue engineering; T. Shinoka --; 18.1; Introduction --; 18.2; Arterial TEVG --; 18.3; Electrospun nanofibers for arterial TEVG --; 18.4; Prevention of thrombosis, stenosis and calcification in arterial TEVG --; 18.5; Current clinical status of TEVG --; 18.6; Summary and perspectives for the future --; 18.7; Conclusion --; References --; 19; Nanofiber composites in blood vessel tissue engineering; S. Ahadian --; 19.1; Introduction --; 19.2; Natural/synthetic nanofiber composites --; 19.3; Synthetic/synthetic nanofiber composites --; 19.4; Conclusion and future perspectives --; References --; 20; Clinical/preclinical aspects of nanofiber composites; M. Ramalingam --; 20.1; Introduction --; 20.2; Status of clinically relevant biomaterials --; 20.3; Clinical and preclinical applications of nanofiber composite materials --; 20.4; Conclusions and future remarks --; Acknowledgements --; References ER -