TY  - BOOK
AU  - Jain,Vimal Kumar
AU  - Priyadarsini,K.Indira
TI  - Organoselenium compounds in biology and medicine: synthesis, biological and therapeutic treatments 
SN  - 9781788010290
AV  - QD412.S5 JAI
U1  - 547.05724 23
PY  - 2018///
CY  - London
PB  - The Royal Society of Chemistry
KW  - Organoselenium compounds
N1  - Includes bibliographical references and index; An overview of organoselenium chemistry: From fundamentals to Synthesis; Looking Beyond the traditional Idea of Glutathione Peroxidase Mimics as Antioxidants; Synthesis of organoselenium compounds with potential biological activities; The Relevant Chemistry of Imidazoline-2-selone Donors with potential Biological Applications; Organoselenium cations: Structures, reactivity and applications; Organoselenium flurophores for probing ROS and heavy metals; Non-bonded selenium…heteroatom interactions in selenoenzymeglutathioneperoxidase (GPx) and mimics; Carbohydrate-derived Organoselenium Compounds: Synthesis and Application in the Structural Analysis of Biomolecules; Reaction of Selenium compounds with reactive oxygen species and the controlof oxidative stress; Reactive selenium species: Redox modulation, antioxidant, antimicrobial and anticancer activities; Ebselen and thioredoxin systems in human health, disease and therapeutic potential; History and development of selenium based radioprotectors: Distinction between inorganic vs. organic forms; Toxicology and anticancer activity of synthetic organoselenium compounds; Metabolism of selenium/selenocystine and their roles in the prevention and treatment of human cancer; Organoselenium compounds as cancer therapeutic agents; Cancer prevention by different forms of selenium

N2  - This book discusses organoselenium chemistry and biology in the context of its therapeutic potential, taking the reader through synthetic techniques, bioactivity and therapeutic applications
ER  -