Nanofiber composites for biomedical applications / edited by Murugan Ramalingam, Seeram Ramakrishna.

Includes bibliographical references and index.

Machine generated contents note: pt. I Introduction to nanofiber composites -- 1. Introduction to nanofiber composites / S. Ramakrishna -- 1.1. Introduction -- 1.2. Classification of nanofiber composites -- 1.3. Properties of nanofiber composites -- 1.4. Fabrication methods of nanofiber composites -- 1.5. Characterization techniques of nanofiber composites -- 1.6. Biomedical applications of nanofiber composites -- 1.7. Clinical translational aspects of nanofiber composites -- 1.8. Commercial aspects of nanofiber composites -- 1.9. Concluding remarks -- References -- pt. II Classification of nanofiber composites -- 2. Ceramic nanofiber composites / M. Ramalingam -- 2.1. Introduction -- 2.2. Types of ceramic nanofiber composite -- 2.3. Properties of ceramic nanofiber composite -- 2.4. Fabrication methods -- 2.5. Biomedical applications of ceramic nanofiber composite -- 2.6. Concluding remarks -- References -- 3. Polymer nanofiber composites / Y.-W. Mai -- 3.1. Introduction -- 3.2. Nanofiber composites using electrospinning -- 3.3. Modified electrospinning setup for scaffold design -- 3.4. Biofunctionalization of fibrous scaffolds -- 3.5. Application of nanofiber composites -- 3.6. Future perspectives of polymer nanofiber -- Acknowledgments -- References -- 4. Metallic nanofiber composites / G. Manivasagam -- 4.1. Introduction -- 4.2. Technological aspect -- 4.3. Metallic nanofiber composite applications in bio-medical and health care -- 4.4. Conclusions and future perspectives -- References -- pt. III Properties of nanofiber composites -- 5. Physicochemical characterization of nanofiber composites / F. Yang -- 5.1. Introduction -- 5.2. Physicochemical characterization at molecular level -- 5.3. Physicochemical characterization at surface level -- 5.4. Physicochemical characterization at materials level -- 5.5. Conclusion -- References -- 6. Mechanical characterization of nanofiber composites / M. Ramalingam -- 6.1. Introduction -- 6.2. Nanotechnology and biomedicine -- 6.3. Tissue engineering -- 6.4. Scaffolds for tissue engineering -- 6.5. Electrospinning -- 6.6. Mechanical properties of nanofibers: case studies -- 6.7. Conclusion and future direction -- Acknowledgment -- References -- 7. Biological characterization of nanofiber composites / D. Sachdev -- 7.1. Introduction -- 7.2. Morphological characterization of nano fibers -- 7.3. Biomedical applications implicated characterization -- 7.4. Cell nanofiber scaffold interactive characterization -- 7.5. Concluding remarks -- References -- pt. IV Biomedical Applications of Nanofiber Composites -- 8. Nanofiber composites in drug delivery / S. Ramakrishna -- 8.1. Introduction -- 8.2. Implications of nanofiber-based DDS in health care -- 8.3. Composite nanofibers for drug delivery -- 8.4. Applications of composite nanofibers as DDS -- 8.5. Future prospects -- 8.6. Concluding remarks -- References -- 9. Nanofiber composites in biomolecular delivery / M. Ramalingam -- 9.1. Introduction -- 9.2. Importance of biomolecules in biomedical applications -- 9.3. Composite nanofibers for biomolecular delivery -- 9.4. Release strategy of biomolecules from composite nanofiber scaffolds -- 9.5. Applications of composite nanofibers for biomolecular delivery -- 9.6. Preclinical status -- 9.7. Concluding remarks -- References -- 10. Nanofiber composites in gene delivery / M. Ramalingam -- 10.1. Introduction -- 10.2. Nanofiber composites-mediated gene delivery -- 10.3. Fabrication methods -- 10.4. Characterization techniques -- 10.5. Classification -- 10.6. Pharmacology and kinetics: gene delivery -- 10.7. Current status -- 10.8. Conclusion -- References -- 11. Nanofiber composites in skin tissue engineering / L. Rajamani -- 11.1. Introduction -- 11.2. Skin morphology -- 11.3. Skin disorders -- 11.4. Wound healing process -- 11.5. Types of skin grafts and skin substitutes -- 11.6. Tissue engineering -- 11.7. Composite Nanofibrous Mats -- 11.8. Impact of nanofibers in skin regeneration process -- 11.9. Conclusion -- Acknowledgment -- References -- 12. Nanofiber composites in bone tissue engineering / A.R. Boccaccini -- 12.1. Introduction -- 12.2. Topic overview -- 12.3. Rationale for the selection of the inorganic phase for bone tissue engineering applications -- 12.4. Electrospinning and its integration with other scaffold fabrication techniques for bone tissue engineering -- 12.5. Three dimensional nanofibrous structures for bone tissue engineering -- 12.6. Functionalized nanofiber composites -- 12.7. In vivo applications of nanofiber composites for bone tissue regeneration -- 12.8. Conclusions -- Acknowledgements -- References -- 13. Nanofiber composites in cartilage tissue engineering / M. Ramalingam -- 13.1. Introduction -- 13.2. Microstructure of cartilage tissue -- 13.3. Composite nanofiber for cartilage regeneration -- 13.4. Biological relevance of composite nanofiber in cartilage regeneration -- 13.5. Future directions and perspectives -- References -- 14. Nanofiber composites in tendon tissue engineering / H. EI-Hamshary -- 14.1. Introduction -- 14.2. Different topological structure of nanofiber for tendon tissue regeneration -- 14.3. Development of three-dimensional scaffolds for tendon tissue engineering -- 14.4. Mechanical simulation of scaffold constructs for tendon tissue remodeling -- 14.5. Growth factors and stem cells strategies incorporated with nanofibers in tendon tissue engineering -- 14.6. Conclusion -- References -- 15. Nanofiber composites in skeletal muscle tissue engineering / J.P. Beier -- 15.1. Introduction -- 15.2. Skeletal muscle anatomy -- 15.3. Tissue engineering of skeletal muscle -- 15.4. Three-dimensional matrices for skeletal muscle tissue engineering -- 15.5. Polymeric Materials for electrospun nanofibers -- 15.6. Mechanical and electrical stimulation of engineered skeletal muscle -- 15.7. Vascularization and in vivo generation of 3D muscle constructs -- 15.8. Future aspects -- 15.9. Conclusion -- References -- 16. Nanofiber composites in neural tissue engineering / H. EI-Hamshary -- 16.1. Introduction -- 16.2. Composite nanofiber NGC -- 16.3. Nanofiber NGC with regular structure -- 16.4. Growth factor incorporated into nanofiber NTE scaffold -- 16.5. Conductive nanofiber NGC and electrical simulation for NTE -- 16.6. Conclusion -- References -- 17. Nanofiber composites in cardiac tissue engineering / D.K. Srinivasan -- 17.1. Introduction -- 17.2. Cardiac structure -- 17.3. Cardiac tissue remodeling -- 17.4. Cardiac tissue engineering -- 17.5. Fibrous scaffolds for building of cardiac tissue -- 17.6. Challenges and future trends in cardiac tissue engineering -- 17.7. Conclusion -- Acknowledgements -- References -- 18. Nanofiber composites in vascular tissue engineering / T. Shinoka -- 18.1. Introduction -- 18.2. Arterial TEVG -- 18.3. Electrospun nanofibers for arterial TEVG -- 18.4. Prevention of thrombosis, stenosis and calcification in arterial TEVG -- 18.5. Current clinical status of TEVG -- 18.6. Summary and perspectives for the future -- 18.7. Conclusion -- References -- 19. Nanofiber composites in blood vessel tissue engineering / S. Ahadian -- 19.1. Introduction -- 19.2. Natural/synthetic nanofiber composites -- 19.3. Synthetic/synthetic nanofiber composites -- 19.4. Conclusion and future perspectives -- References -- 20. Clinical/preclinical aspects of nanofiber composites / M. Ramalingam -- 20.1. Introduction -- 20.2. Status of clinically relevant biomaterials -- 20.3. Clinical and preclinical applications of nanofiber composite materials -- 20.4. Conclusions and future remarks -- Acknowledgements -- References.